A CHEMICAL-GENETIC STRATEGY REVEALS DISTINCT TEMPORAL REQUIREMENTS FOR SAD-1 KINASE IN NEURONAL POLARIZATION AND SYNAPSE FORMATION

A chemical-genetic strategy reveals distinct temporal requirements for SAD-1 kinase in neuronal polarization and synapse formation

Abstract Background Neurons assemble into a functional network through a sequence of developmental processes including neuronal polarization and synapse formation.In Caenorhabditis elegans, the serine/threonine SAD-1 kinase is essential for proper neuronal polarity and synaptic organization.To determine if SAD-1 activity regulates the establishment

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An Investigation into the Nature and Basis of Contractual Liability; A Comparative Study of Islamic and Western Law

Contractual liability in the strict sense of the word is the obligation to compensate for damages arised Horn Bags from breach of contract.The main question is about the nature and basis of this obligation.Shall we consider it as a form of compliance of the contract; meaning that promisor has to give the equivalent of the contract to aggrieved part

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